New technique allows research of nano-sized particles
[ad_1]
Researchers at Karolinska Institutet have created a brand new technique of learning the smallest bioparticles within the physique. The research, which is revealed in Nature Biotechnology, has appreciable scientific potential, reminiscent of within the growth of simpler vaccines.
Circulating across the physique are nanoparticles that have an effect on it in a method or one other. For instance, there are lipoproteins that keep cell metabolism, pathogenic viruses that trigger many illnesses and lipid nanoparticles which might be used to hold medication, like latest lipid nanoparticle-based mRNA vaccines.
Nevertheless, such particles are too small to be studied simply. To allow this, the researchers on this research have developed a brand new technique that they name single-particle profiling (SPP).
“We’re presenting a brand new technique that offers unprecedented details about nano-sized particles,” says the research’s final creator assistant professor Erdinc Sezgin at SciLifeLab and the Division of Ladies’s and Youngsters’s Well being, Karolinska Institutet.
The strategy makes it doable to measure the content material and properties of 1000’s of particles between 5 and 200 nanometers in dimension.
“Our technique can be utilized to check bioparticles in well being and illness.” says Dr. Sezgin. “Furthermore, it is going to even be a useful instrument in creating higher and simpler nanocarriers.”
One of many researchers’ objectives was to create a easy, cheap technique accessible to all researchers.
“We established a way based mostly on commercially accessible microscopes and made our data-analysis instrument and all our information freely accessible,” says Dr. Sezgin.
Extra info:
Taras Sych et al, Excessive-throughput measurement of the content material and properties of nano-sized bioparticles with single-particle profiler, Nature Biotechnology (2023). DOI: 10.1038/s41587-023-01825-5. www.nature.com/articles/s41587-023-01825-5
Offered by
Karolinska Institutet
Quotation:
New technique allows research of nano-sized particles (2023, June 12)
retrieved 12 June 2023
from https://phys.org/information/2023-06-method-enables-nano-sized-particles.html
This doc is topic to copyright. Aside from any truthful dealing for the aim of personal research or analysis, no
half could also be reproduced with out the written permission. The content material is supplied for info functions solely.
[ad_2]